Certain medications increase the risk of hyperglycemia, including corticosteroids,
octreotide, beta blockers, epinephrine, thiazide diuretics, niacin, pentamidine, protease inhibitors,
L-asparaginase, and some antipsychotic agents. The acute administration of stimulants
such as amphetamine typically produces hyperglycemia; chronic use, however,
produces hypoglycemia. Some of the newer psychotropic medications, such
as Zyprexa (Olanzapine) and Cymbalta (Duloxetine), can also cause significant hyperglycemia.
Thiazides are used to treat type 2 diabetes but it also causes severe hyperglycemia.
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